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Bone mineral density changes in the knee after meniscal allograft transplantation. A 2-year follow-up.

Recruiting
Conditions
A potential chondroprotective effect of meniscal allograft transplantation (MAT) remains still unclear. Subchondral bone mineral density (BMD) and subchondral bone remodelling play important roles in the development of osteoarthritis. The purpose of our study was to determine BMD changes after MAT during a 2 year follow-up. BMD changes between the operated and the non-operated knee, as well as correlation between BMD, bone scintigraphy and Knee injury and Osteoarthritis Outcome Score (KOOS) were determined.
Registration Number
NL-OMON20552
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
26
Inclusion Criteria

disabling unicompartmental pain after a (sub)total meniscectomy, patient under the age of 55 years, stable knee joint or stabilized by concomitant ACL reconstruction (ACLR) and normal knee alignment.

Exclusion Criteria

grade IV chondropathy, PCL insufficiency, abnormal and uncorrected knee or lower limb alignment, chronic pain syndrome of the knee, arthrofibrosis, muscular atrophy and a history of knee sepsis.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Bone mineral density, semi-quantitatively bone scan scores
Secondary Outcome Measures
NameTimeMethod
Knee injury and Osteoarthritis Outcome Score (KOOS)
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