Effects of HMG-CoA-reductase inhibition (atorvastatin) on renal sodium excretion, renal hemodynamics, tubular function and vasoactive hormones in healthy subjects under diet with normal and high sodium content.
- Conditions
- Healthy volunteer trial
- Registration Number
- EUCTR2006-005143-28-DK
- Lead Sponsor
- Medicinsk Forskning
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Men and women, age 20-50 years, BMI<30, for women use of anticonception
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Clinical or anamnestic signs of disease of the heart, lungs, kidney, liver, brain or endocrine organs; abnormal findings at bloodscreening (hemoglobin, sodium, potassium, albumin, creatinin, bloodsugar, bilirubin, alaninaminotransferease, basic phosphatase); albuminuri; glucose in urine; cancer, hypertension, addiction to alcohol; medical treatment except per oral anticonception; pregnancy or breastfeeding; blooddonation one month before the trail.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method