A study on comparison of the effect of intravenous Tranexamic acid and sublingual Misoprostol in reducing blood loss during caeserean sectio
Phase 2
- Conditions
- Health Condition 1: O60-O77- Complications of labor and delivery
- Registration Number
- CTRI/2024/05/067355
- Lead Sponsor
- SRI MANAKULA VINAYAGAR MEDICAL COLLEGE AND HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Term pregnancy more than or equal to 37 weeks of gestation.
2.Singleton pregnancy undergoing emergency / elective caeserean section.
Exclusion Criteria
1.Antepartum hemorrhage( abruptio placenta, placenta previa)
2.Any underlying disease ( Heart, Liver, Pulmonary)
3.Allergic to Tranexamic acid and Misoprostol
4.Coagulation disorders.
5.Intrauterine fetal demise
6.Fibroid
7.DIC, Anticoagulant therapy
8.Previous history of uterine rupture
9.Multiple pregnancy.
10.Polyhydramnios
11.Category 1 caeserean section ( example: cord prolapse)
12.Caeserean section under general anesthesia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of Intravenous Tranexamic acid and sublingual Misoprostol in reducing blood loss during Caeserean sectionTimepoint: 1.Blood loss during Caeserean section,which is assessed by Soaked mop count and by suction volume excluding the amniotic fluid <br/ ><br>2. Post opertaive hemoglobin and hematocrit after 48 hours. <br/ ><br>3.Total amount of blood loss 48 hours post surgery
- Secondary Outcome Measures
Name Time Method 1.To compare the safety profile of both drugs. <br/ ><br>2.To assess if there is need for any additional uterotonic usage / blood transfusion.Timepoint: Post operative hemoglobin d hematocrit after 48 hours.