Removal of Erroneous Penicillin Allergy Labels: Implementation Study (REPeAL)
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The proportion of patients admitted to adult medical, surgical and critical care specialities with a penicillin allergy record, where the allergy record is preventing first line antibiotic therapy, that are safely de-labelled.
研究概览
简要总结
To test the implementation of penicillin allergy de-labelling delivered by the responsible clinical teams and the antimicrobial stewardship teams across all medical, surgical and critical care specialities in a UK hospital using the developed toolkit and a validated penicillin allergy decision support tool.
详细描述
Aim:
To test implementation of the penicillin allergy de-labelling complex intervention in surgical, medical and critical care patient pathway.
Objectives:
- To use the Institute for Health Improvement (IHI) Model for Improvement methodology to implement the penicillin allergy de-labelling complex intervention in each setting (surgery, medicine, critical care)
- To measure the number of patients meeting inclusion criteria (>16 with a penA not prescribed first line antibiotics) who have had their penicillin allergy record assessed by the wider clinical teams and separately by the AMS team.
- To measure the patient uptake of penicillin allergy record removal (i.e. the rate of patient declining de-label / DOC).
To interview 10-15 patients and 10-15 healthcare workers to gain insight into the penicillin allergy de labelling process.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult (>16) patients admitted to hospital over the study period with a penicillin allergy record preventing first line antibiotic use.
排除标准
- 未提供
结局指标
主要结局
The proportion of patients admitted to adult medical, surgical and critical care specialities with a penicillin allergy record, where the allergy record is preventing first line antibiotic therapy, that are safely de-labelled.
时间窗: 1 year
次要结局
未报告次要终点