To see the effect of Basti and Virechana in Scleroderma
Phase 2
- Conditions
- Health Condition 1: M341- CR(E)ST syndrome
- Registration Number
- CTRI/2021/07/035099
- Lead Sponsor
- PATANJALI AYURVED COLLEGE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Age 20-60 years; 2. Patients fulfil the criteria of Vatarakta (Scleroderma); 3. Patients with Limited Cutaneous Systemic Sclerosis (LCSS); 4. CREST (Calcinosis, Raynaudâ??s, Oesophageal involvement, Sclerodactyly and Telangiectasia) Syndrome; 5. Chronicity between 6 weeks to 10 years with not less than 30% involvement of body surface.; 6. Digital Ulcers; 7. Patients who are fit for Basti Karma and Virechana Karma
Exclusion Criteria
1. Age less than 20 and more than 60 years; 2. Diffuse Cutaneous Systemic Sclerosis; 3. Patients with traumatic, malignant and chronic wound; 4. Pregnancy & lactating mothers; 5. Any other systemic disorders; 6. Patients who are unfit for Basti Karma and Virechana Karma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Subjective parameters: <br/ ><br>1.Twak Kathinta (Skin Hardening) <br/ ><br>2.Twak Vaivarnyata (Raynaudâ??s Phenomenon) <br/ ><br>3.Sandhishotha (Joint Swelling) <br/ ><br>4.Stabdhata (Stiffness) <br/ ><br>5.Paka / Twak Lohita (Digital Ulcer) <br/ ><br> <br/ ><br>Associated Symptoms: <br/ ><br>1.Shula (Pain) <br/ ><br>2.Kandu (Itching) <br/ ><br>3.Daha (Burning sensations) <br/ ><br>4.Jwara (Fever)Timepoint: 30 days
- Secondary Outcome Measures
Name Time Method Objective parameters: <br/ ><br>1.Modified Rodnan Skin Score (mRSS) <br/ ><br>2.Involvement of Body Surface Area <br/ ><br>3.Digital Ulcer Size <br/ ><br>4.Discharge <br/ ><br>5.ESR <br/ ><br>6.Antinuclear Antibody Titers <br/ ><br>7.CRPTimepoint: 30 days