Safety of Remifentanil Infusion

Phase 4

Completed

• Conditions: Urinary Tract Problem
• Interventions: Drug: remifentanil

• Registration Number: NCT01303627
• Lead Sponsor: Diskapi Teaching and Research Hospital

Brief Summary

The effect of maintenance remifentanil infusion with target controlled infusion during laryngeal mask airway removal on hemodynamic parameters and emergence quality is going to be investigated.

Detailed Description

In all patients (control group and remifentanil group induction of anesthesia will be achieved with desflurane and remifentanil.Anesthesia will be maintained with remifentanil (1-4 ng/mL) by TCI target controlled infusion, and desflurane . Throughout the surgery hemodynamic parameters are going to be recorded. As soon as the surgery has been finished, in control group remifentanil infusion and desflurane inhalation is going to be stopped.In remifentanil group,desflurane inhalation is going to be stopped and remifentanil infusion will be maintained until the removal of LMA. During the emergence period the time of eye opening, hemodynamic parameters and emergence quality (score 1-2)are going to be recorded.

Study Timeline

• Study Start: 2011-02
• Study First Submitted: 2011-02-24
• Study First Submitted QC: 2011-02-24
• Study First Posted: 2011-02-25
• Primary Completion: 2011-03
• Study Completion: 2011-04
• Results First Submitted: 2012-01-30
• Results First Submitted QC: 2012-05-17
• Status Verified: 2012-06
• Last Update Submitted: 2012-06-15
• Results First Posted: 2012-06-18
• Last Update Posted: 2012-06-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• ASA I-II status
• aged 18-60 years old
• presenting for ureterorenoscopy

Exclusion Criteria

• history of hypertension
• asthma and chronic obstructive lung disease
• recent respiratory tract infections

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ultiva,remifentanil,opioid,analgesic	remifentanil	Remifentanil:1.5ng/ml remifentanil infusion maintained at the end of the surgery

Primary Outcome Measures

Name	Time	Method
Smooth cLMA Removal Condition (Score 1)	At the end of the surgery	cLMA removal was accepted as successful (score 1) if none of the complications coughing, teeth clenching, gross purposeful movements, breath holding, laryngospasm, and desatura- tion to SpO2\\90% was observed. If any of these compli- cations was observed it was regarded as unsuccessful (score 2)

Trial Locations

Locations (1)

Ministry of Health Diskapi Yildirim Beyazit Research and Training Hospital departement of 1. Anesthesiology; 🇹🇷 Ankara, Turkey