Effect of Laghu-vaishvanar Churna and Dhanya Nagar kwath in management of Sublinical Hypothyroidism

Phase 2

• Conditions: Health Condition 1: E039- Hypothyroidism, unspecified

• Registration Number: CTRI/2022/04/041744
• Lead Sponsor: Ayurvedic and Unani Tibbia College Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 2 May 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patient willing to participate in the trial and sign the consent form.

2. The patients between the age group of 18 to 60 years in either sex.

3. Patients of subclinical hypothyroidism with features mentioned in subjective parameters.

4. On the basis of raised serum TSH(5-10 μIU/ml) and normal serum T4 level.

Exclusion Criteria

1. Patients who were not willing for trial.

2. TSH level more than 10 or less than 5 μIU/ml.

3. Patient with presenting sign of moderate to severe or unmanageable bradycardia ( <50bpm)

4. Patients who are suffering from hypothyroidism for more than 10 year.

5. Patients suffering from any other systemic illness Diabetes, HTN, liver disorder, tuberculosis etc.

6. Pregnant and lactating patients.

7. Patients taking antibiotic therapy for any systemic illness within 2 months.

8. H/O of hypersensitivity of any trial drug.

9. Patient who fail to give consent.

10. Patients with genetic disorder, chronic disorder like paralysis, cancer, renal failure, hepatic failure and

IHD.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in Subjective parameters <br/ ><br> <br/ ><br>1. Weakness (Grade 0-3) <br/ ><br>2. Dry skin (Grade 0-3) <br/ ><br>3. Feeling cold (Grade 0-3) <br/ ><br>4. Constipation (Grade 0-3) <br/ ><br>5. Poor apetite (Grade 0-3) <br/ ><br>6. Dyspnea (Grade 0-3) <br/ ><br>7. Hoarse voice (Grade 0-3) <br/ ><br>8. Menorrhagia (Grade 0-3) <br/ ><br>9. Paraesthesia (Grade 0-3) <br/ ><br>10. Weight gain (Grade 0-3)Timepoint: At baseline and at 3 months

Secondary Outcome Measures

Name	Time	Method
Changes in Thyroid Profile i.e. T3, T4, TSH valuesTimepoint: At baseline and at 3 months