Surveillance of vascular access by means of physical examination to detect signs which suggest the presence of dysfunction, which include changes in Kt/V ( quantifies treatment adequacy) measurement or changes in other clinical parameters in patients who are on dialysis.
- Conditions
- Health Condition 1: N186- End stage renal diseaseHealth Condition 2: Z00-Z99- Factors influencing health status and contact with health services
- Registration Number
- CTRI/2018/11/016325
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1) Patient on dialysis > 2 times per week with mature upper extremity AVF/ AVG in use for 1 month or more which is able to provide flow rates of > 250 ml/min sustained for a period of 4 weeks or more.
2) Tunnel catheter with good flows for 2 weeks can be included
3) No access flow issues prior to inclusion in study (flow rates of 250ml / minutes and above can be achieved consistently for a period of 4 weeks) and patients with prior history of AV access angiography or angioplasty with functional AV access (post intervention flow rates of > 250 ml/min sustained for a period of 4 weeks or more)
4) Adult population between ages of 18-65 years will be included in study
1)Patients with documented procoagulant state.
2)Patients with more than 2 primary access failures
3)Inability to provide consent
4)Patient of acute kidney injury and patients planned for transplant in next 6 months
5)Patients of congestive heart failure (defined as EF < 40% documented on echocardiography in the last 6 months, advanced chronic liver disease and known lower extremity peripheral vascular disease)
6)Patients needing more than standard dose of Heparin
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To develop a low cost, efficient system for Vascular Access Surveillance for developing countriesTimepoint: Baseline and quarterly four visits
- Secondary Outcome Measures
Name Time Method To study the efficacy of VAS system in detecting AVF and AVG dysfunction <br/ ><br> <br/ ><br>Timepoint: Baseline and quarterly four visits