JPRN-UMIN000013502
Completed
未知
Phase II study of erlotinib as first line chemotherapy in patients with lung adenocarcinoma with brain metastasis and EGFR mutations. - Phase II study of erlotinib as first line chemotherapy in patients with lung adenocarcinoma with brain metastasis and EGFR mutations.
Conditionslung adenocarcinoma
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- lung adenocarcinoma
- Sponsor
- Osaka city General Hospital
- Enrollment
- 25
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\)Symptomatic brain metastasis. 2\)Patients with untreated brain metastases of size 3cm or more. 3\)Active synchronous malignant neoplasm. 4\)Uncontrolled pleural effusion, ascites, or pericardial effusion. 5\)Active infection requiring systemic administration of antiviral agents, antifungal agents, or antibiotics. 6\)Severe complications. 7\)Interstitial pneumonia or pulmonary fibrosis detectable on Xray. 8\)History of severe drug allergy 9\)Patients unable to be treated with oral medication. 10\)Pregnancy or lactating patients. 11\)Uncontrolled psychotic disease. 12\)Patients who were judged inappropriate to entry this study by physician.
Outcomes
Primary Outcomes
Not specified
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