CTRI/2017/07/008996招募中未知
Carvedilol, Endoscopic Variceal Ligation or combination of both for prevention of First Variceal Bleed in Childâ??s B & C Cirrhosis - A Randomized Controlled Trial
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 330
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1) Liver Cirrhotics between 18 to 70 years of age (cirrhosis diagnosed on the basis of clinical, biochemical, fibroscan and imaging.)
- •2) CTP more than equals to 7 to 15.
- •3) Small esophageal varices with RCS and large esophageal varices (more than 5 mm)
- •4) No history of previous bleed
排除标准
- •1) Malignancy-HCC, PVT
- •2) Child A
- •3) MELD >35
- •4) Contraindications to β blockers.
- •5) Platelet count < 30,000/mm3
- •6)Previous endoscopic variceal treatment. (Beyond 21 days)
- •7) Patients having an indication for TIPS or requiring more than 1 therapeutic ascitic tapping/month
- •8) Post TIPS, Shunt surgery
- •9)Acute kidney injury (Sr.Cr >1.5mg/dl)
- •10) Non cirrhotic portal hypertension
- •11) Acute on chronic liver failure
研究者
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