Probiotics in the management of eczema

Phase 4

Recruiting

• Conditions: ATOPIC DERMATITIS; Skin - Dermatological conditions

• Registration Number: ACTRN12605000615684
• Lead Sponsor: The Women's & Children's Hospital (part of the Children, Youth and Women's Health Service)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-10-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Eczema - SCORAD of 15 or greaterGuardian's proficient in EnglishNot previously actively treated with probiotics for eczema. No current chronic illness other than asthma, allergic, rhinitis or food allergy.

Exclusion Criteria

No exclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
SCORAD (SCORing Atopic Dermatitis Clinical Score)[Measured at week 0, week 8 and week 16.]

Secondary Outcome Measures

Name	Time	Method
Gut permeability using intestinal sugar permeability test.[All secondary outcomes are measured at: subject commencement; at 2 months (treatment completion) and at 4 months (subject completion).];IL2, TNFa, IFNg, IL4, IL5, IL10, TGFb.[All secondary outcomes are measured at: subject commencement; at 2 months (treatment completion) and at 4 months (subject completion).];CCR4/CLA expression on CD4 cells. [All secondary outcomes are measured at: subject commencement; at 2 months (treatment completion) and at 4 months (subject completion).]