NCT03428165已完成不适用
Transfer of Frozen Embryos in NATural Cycle: Evaluation of Impact of Spontaneous Versus HCG-triggered Ovulation on Pregnancy Rate - Bicentric Prospective Open Randomized Controlled Trial
Centre Hospitalier Universitaire de Nīmes4 个研究点 分布在 1 个国家目标入组 103 人开始时间: 2018年3月7日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 103
- 试验地点
- 4
- 主要终点
- Pregnancy rate after transfer of frozen embryos at day 14 between groups
研究概览
简要总结
The purpose of the study is to evaluated whether there is a difference in pregnancy rate when transferring frozen embryos between patietns having spontaneously ovulated versus those triggered to voulate with HCG.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •The patient must have given their free and informed consent and signed the consent form
- •The patient must be a member or beneficiary of a health insurance plan
- •The patient is aged between 18 and 40
- •Patient has regular cycles and classified as 'easy' for transfer of a frozen embryo at blastocyste stage (vitrification day 5)
排除标准
- •The subject is participating in an interventional study, or is in a period of exclusion determined by a previous study
- •The subject refuses to sign the consent
- •It is impossible to give the subject informed information
- •The patient is under safeguard of justice or state guardianship
- •Patient using donated oocytes
- •Necessity of pre-implantation diagnosis
- •Patients with stage 3 or 4 endometriosis or adenomyosis
结局指标
主要结局
Pregnancy rate after transfer of frozen embryos at day 14 between groups
时间窗: Day 14
Yes/no; Blood ßHCG \> 100UI/L
次要结局
- Pregnancy rate at week 12(Week 12)
- Miscarriage rate within first 12 weeks(Week 12)
- Cancellation of transfer due to premature ovulation (progesterone >3ng/ml and/or Luteinizing hormone > 3-fold base level)(Day 0)
- Number of visits for endometrial preparation until attaining LH peak(Day 0)
- Pregnancy term(At delivery, maximum week 42)
- Birth weight(At delivery, maximum week 42)
- Live birth(At delivery, maximum week 42)
研究者
研究点 (4)
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