Locked-in Syndrome Caused by Pulmonary Arteriovenous Malformation: A Case Report

• Conditions: Locked-In Syndrome；Pulmonary Arteriovenous Malformation

• Registration Number: NCT05348902
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

In this case, we report a case of atresia syndrome (LIS), a serious neurological disease caused by pulmonary arteriovenous fistula (PAVM). We present a previously healthy middle-aged woman who developed atresia syndrome after severe pontine infarction due to basilar artery occlusion due to undiagnosed arteriovenous malformation. This report reviewed the medical history, post-admission examination and related literature, and concluded that PAVM should be considered as the cause of implicit stroke, especially in young patients with right-to-left shunt, and should be actively treated.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-10
• Study Start: 2021-10-01
• Study First Submitted: 2022-04-10
• Study First Submitted QC: 2022-04-26
• Last Update Submitted: 2022-04-26
• Study First Posted: 2022-04-27
• Last Update Posted: 2022-04-27
• Primary Completion: 2022-06-02
• Study Completion: 2022-06-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• A case of Locked-in syndrome due to pulmonary arteriovenous malformation

Exclusion Criteria

• Patients or family members objected to the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Locked-in syndrome caused by pulmonary arteriovenous malformation . Check list report	1month	A recommendation is made for the treatment and prognosis of patients with severe atresia caused by arteriovenous fistula.

Trial Locations

Locations (1)

2nd Affiliated Hospital, School of Medicine, Zhejiang University, China; 🇨🇳 Hangzhou, China