The effect of Glycyrrhiza glabra vaginal cream on treatment of vaginal atrophy of postmenopausal wome
Not Applicable
- Conditions
- Vaginal atrophy.Postmenopausal Atrophic Vaginitis
- Registration Number
- IRCT2017010331739N1
- Lead Sponsor
- Vice chancellor for research, Ahwaz Judishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
Women with sexual activity and single partner; passing at least 12 months of amenorrhea; presence of vaginal atrophy symptoms; normal blood pressure.
Exclusion criteria: Genital abnormalities; breast diseases with unknown reason; liver cholestatic disorders; renal failure; vaginal infection needing treatment; genital bleeding or spotting with unknown reason; hormone therapy or using sex hormones within the 2 months before the study; using of phytoestrogens such as soy, red clover, fenugreek, and vitex within the last one month; body mass index more than 30 kilogram per cubic meter.
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Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vaginal acidity. Timepoint: Before and after intervention. Method of measurement: By PH strip.;Subjectiv symptoms of vaginal atrophy. Timepoint: Before intervention and two, four and eight weeks after the intervention. Method of measurement: Kupperman index questionnaire.;Dyspareunia. Timepoint: Before intervention and two, four and eight weeks after the intervention. Method of measurement: Dyspareunia self-administered scale.;Vaginal dryness. Timepoint: Before intervention and two, four and eight weeks after the intervention. Method of measurement: Vaginal dryness self-administer scale.;Percent of vaginal cells maturation. Timepoint: Before and after intervention. Method of measurement: Vaginal smear.
- Secondary Outcome Measures
Name Time Method Sexual function. Timepoint: Before and after intervention. Method of measurement: Female sexual function index questionnaire.;Sexual satisfaction. Timepoint: Before and after intervention. Method of measurement: Larson's sexual satisfaction questionnaire.