Effects of Non-invasive Brain Stimulation in Impulse Control Disorders

Not Applicable

• Conditions: Impulse Control Disorder
• Interventions: Device: Noninvasive brain stimulation

• Registration Number: NCT02927002
• Lead Sponsor: Laval University

Brief Summary

The goal of this project is to study the effect of noninvasive brain stimulation on decision-making and on brain activity in impulse control disorders.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-10
• Study First Submitted: 2016-05-17
• Study First Submitted QC: 2016-10-05
• Study First Posted: 2016-10-06
• Status Verified: 2017-10
• Last Update Submitted: 2017-10-06
• Last Update Posted: 2017-10-09
• Primary Completion: 2017-12
• Study Completion: 2018-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Impulse control disorders according to DSM-IV criteria

Exclusion Criteria

• Other psychiatric disorders
• Contraindication to Non-invasive brain stimulation and MRI

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Noninvasive brain: sham	Noninvasive brain stimulation	In sham condition, subject will receive stimulation only at the beginning and at the end of 30-minute stimulation period.
Noninvasive brain stimulation: active	Noninvasive brain stimulation	In active condition, subject will receive stimulation during all the 30-minute stimulation period

Primary Outcome Measures

Name	Time	Method
Change in decision-making from pre to post stimulation assessed with the Balloon Analogue Risk Task	10 minutes before and immediately after the 30 minutes of non invasive brain stimulation

Secondary Outcome Measures

Name	Time	Method
Changes in brain activity assessed between before and during stimulation measured with functional magnetic resonance (fMRI)	20 minutes before and immediately after the 30 minutes of non invasive brain stimulation
Neural metabolites concentrations measured with magnetic resonance spectroscopy (MRS)	20 minutes before and immediately after the 30 minutes of non invasive brain stimulation
Change in Craving from pre to post stimulation assessed with a single standardized scale	7 minutes before and 3 minutes after the end of the 30 minutes of non invasive brain stimulation

Trial Locations

Locations (1)

Centre Interdisciplinaire de Recherche en Réadaptation et Intégration; 🇨🇦 Québec, Quebec, Canada