Assessing the Health Impact of a Combined Water and Sanitation Intervention in Rural Odisha, India

• Conditions: Diarrhea; Enteric Infection; Soil-transmitted Helminth Infection; Stunting
• Interventions: Behavioral: Improved water supply and sanitation

• Registration Number: NCT02441699
• Lead Sponsor: London School of Hygiene and Tropical Medicine

Brief Summary

This is a matched-cohort study designed to assess the health impact of a rural demand-driven water and sanitation intervention that provides piped treated water and household level pour-flush latrines and bathing rooms, as implemented by Gram Vikas.

Detailed Description

We will undertake a matched-cohort study among 84 villages in Ganjam district, Orissa, India to assess the health impact of a program that provides improved water supplies and sanitation to rural villages.

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2015-04-27
• Study First Submitted QC: 2015-05-07
• Study First Posted: 2015-05-12
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-20
• Last Update Posted: 2019-08-21
• Primary Completion: 2019-12
• Study Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2940

Inclusion Criteria

• Households in participating villages will be eligible to participate in the study if they have at least one child under 5 years.

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Intervention group	Improved water supply and sanitation	Rural villages in which Gram Vikas has fully implemented its water supply and sanitation (Mantra) intervention. Intervention villages must: 1) be within 3 hours travel to the study office in Brahmapur, 2) have started the intervention by January 2003, and 3) have completed the intervention by January 2013.

Primary Outcome Measures

Name	Time	Method
Reported diarrhoea in children <5 years	7-day recall, assessed 4 times during 3-month follow-up rounds

Secondary Outcome Measures

Name	Time	Method
Soil-transmitted helminth infection	Point prevalence assessed in rounds 2 (approximately 90-120 days after study commencement) and 4 (approximately 240 to 360 days after study commencement)	Stool samples taken and assayed for ascaris, trichuris, hookworm
Reported lower respiratory infection in children <5	7-day recall, assessed 4 times during 3-month follow-up rounds
Diarrhoea among all ages	7-day recall, assessed 4 times during 3-month follow-up roundsits
Lower respiratory infection among all ages	7-day recall, assessed 4 times during 3-month follow-up roundsts
Biomarkers of environmental enteropathy and enteric infection	Assessed once during round 3 (approximately 180 to 240 days following commencement of study
Height-for-age among children < 2 years	Assessed approximately every 90 days for a total of four measurement over study period	Children height measured and HAZ scores computed
Weight-for-age among children <5	Assessed approximately every 90 days for a total of four measurement over study periodAssessed during all four follow up rounds	Children weighed and WAZ scores computed

Trial Locations

Locations (1)

London School of Hygiene & Tropical Medicine; 🇬🇧 London, United Kingdom