Effects of Left Atrial Pressure-guided Ventricular Rate Regulation on Cardiac Function in Patients Therapy With Atrioventricular Node Ablation Combined With Left Bundle Branch Pacing
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Atrial Fibrillation
- Sponsor
- Shanghai 10th People's Hospital
- Enrollment
- 140
- Locations
- 1
- Primary Endpoint
- EF%
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Effects of left atrial pressure-guided ventricular rate changes on cardiac function after atrioventricular node ablation combined with left bundle branch pacing
Detailed Description
Effects of left atrial pressure-guided ventricular rate changes on cardiac function after atrioventricular node ablation combined with left bundle branch pacing. For patients with non-valvular atrial fibrillation who received atrioventricular node ablation combined with left bundle branch pacing in our hospital, a left atrial pressure catheter was used to monitor atrial pressure during the operation, and a lower average atrial pressure was obtained by adjusting the pacing frequency of the pacemaker. In a randomized controlled manner, the postoperative echocardiography, cardiothoracic ratio, cardiac function, etc. were compared between patients without atrial pressure monitoring and those who received atrial pressure adjustment, in order to clarify the effect of left atrial pressure-guided ventricular rate adjustment on atrioventricular node ablation combined with left bundle Benefit of pacing patients.
Investigators
Ya-Wei Xu
Director of Cardiology
Shanghai 10th People's Hospital
Eligibility Criteria
Inclusion Criteria
- •18-85 years old atrial fibrillation patients
Exclusion Criteria
- •There is a history of pacemaker implantation; patients after coronary artery bypass grafting; severe coronary stenosis or occlusion cannot be treated with reperfusion;
Outcomes
Primary Outcomes
EF%
Time Frame: 1-year
aortic vestibular ejection fraction
Secondary Outcomes
- Hospitalizations for heart failure(1 years)
- cardiovascular all-cause mortality(1week)