A Systematic Ultrasound Assessment During Intubation Procedure to Predict Cardiovascular Collapse Related to Intubation in the Intensive Care Unit: a Prospective, Multiple-center Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 3
- 主要终点
- Subsequent cardiovascular collapse related to intubation
研究概览
简要总结
In the operating room, most intubation procedures (IP) are scheduled and performed on hemodynamically stable patients. In the ICU, IP is frequently performed in emergent patients, because of unstable hemodynamics and/or acute respiratory failure, and complicated by a subsequent cardiovascular collapse. Transthoracic echocardiography (TTE) has become readily available in most ICUs for several years. Echocardiography enables to perform a noninvasive hemodynamic evaluation (cardiac function and volemia status).
We hypothesized that performing a TTE prior to IP may help to predict cardiovascular collapse and its components.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient requiring endotracheal intubation
排除标准
- •Age < 18 yrs
- •Pregnancy
- •Amputation of a lower limb
- •Passing leg raising contraindication: intracranial hypertension with invasive monitoring, fracture of the pelvis or limbs
- •Patients under administrative protective measures
- •Severe cardiovascular collapse before intubation
- •Severe cardiogenic pulmonary oedema
结局指标
主要结局
Subsequent cardiovascular collapse related to intubation
时间窗: Within 15 minutes of intubation
Mean arterial pressure drop \< 60 mmHg
次要结局
- Ultrasound parameters to predict fluid responsiveness(30 minutes before intubation, less than 30 minutes after intubation, 1 minutes after lifting legs and 3 hours after intubation)