A Systematic Ultrasound Assessment During Intubation Procedure to Predict Cardiovascular Collapse Related to Intubation in the Intensive Care Unit: a Prospective, Multiple-center Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Intubation
- Sponsor
- University Hospital, Brest
- Enrollment
- 70
- Locations
- 3
- Primary Endpoint
- Subsequent cardiovascular collapse related to intubation
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
In the operating room, most intubation procedures (IP) are scheduled and performed on hemodynamically stable patients. In the ICU, IP is frequently performed in emergent patients, because of unstable hemodynamics and/or acute respiratory failure, and complicated by a subsequent cardiovascular collapse. Transthoracic echocardiography (TTE) has become readily available in most ICUs for several years. Echocardiography enables to perform a noninvasive hemodynamic evaluation (cardiac function and volemia status).
We hypothesized that performing a TTE prior to IP may help to predict cardiovascular collapse and its components.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient requiring endotracheal intubation
Exclusion Criteria
- •Age \< 18 yrs
- •Pregnancy
- •Amputation of a lower limb
- •Passing leg raising contraindication: intracranial hypertension with invasive monitoring, fracture of the pelvis or limbs
- •Patients under administrative protective measures
- •Severe cardiovascular collapse before intubation
- •Severe cardiogenic pulmonary oedema
Outcomes
Primary Outcomes
Subsequent cardiovascular collapse related to intubation
Time Frame: Within 15 minutes of intubation
Mean arterial pressure drop \< 60 mmHg
Secondary Outcomes
- Ultrasound parameters to predict fluid responsiveness(30 minutes before intubation, less than 30 minutes after intubation, 1 minutes after lifting legs and 3 hours after intubation)