Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.

Completed

• Conditions: Impacted Third Molar Tooth
• Interventions: Diagnostic Test: Diagnoses; Procedure: traditional osteotomies; Biological: platelet rich fibrin; Drug: Antibiotics, Penicillin; Device: low laser therapy, bicure laser; Drug: Analgesic

• Registration Number: NCT06262945
• Lead Sponsor: Beste Erismen

Brief Summary

The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction. The study included a total of 60 patients with impacted mandibular third molar. Patients were evaluated in 4 randomly separated groups. In group 1, PRF was applied to the tooth socket. In group 2, PRF was applied to the tooth socket combined with Low Laser Treatment extraorally to the extraction area for three days within surgery day In group 3, Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day. In group 4 (control group), tradional osteomy was made. The outcome variables were pain, swelling, the number of analgesics taken, and trismus. These variables were also assessed based on first, second, third, and seventh days following the operation. All of the 4 groups patients were prescribed an 875/125 mg amoxicillin/clavulanic acid tablet twice daily for five days.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-02
• Status Verified: 2024-02
• Primary Completion: 2024-02-06
• Study Completion: 2024-02-07
• Study First Submitted: 2024-02-08
• Study First Submitted QC: 2024-02-15
• Last Update Submitted: 2024-02-15
• Study First Posted: 2024-02-16
• Last Update Posted: 2024-02-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• The patient had no systemic diseases, no taken opioids for a long period, no current infections or acute pericoronitis, no smoke or drink alcohol, no pregnancy, the absence of allergy to penicillin and presence of penicillin allergy.

Exclusion Criteria

• pericoronitis, no inflammation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 2	Analgesic	platelet rich fibrin placed in to the socket of the extractraciton tooth combined with low laser treatment extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 1	traditional osteotomies	platelet rich fibrin placed into the socket of the extraciton tooth + Augmentin 1gr tablet prescribed 2 times a day
Group 1	Antibiotics, Penicillin	platelet rich fibrin placed into the socket of the extraciton tooth + Augmentin 1gr tablet prescribed 2 times a day
Group 2	traditional osteotomies	platelet rich fibrin placed in to the socket of the extractraciton tooth combined with low laser treatment extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 3	Diagnoses	Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Control group.	Diagnoses	Tradional osteomy was made. + Augmentin 1gr tablet prescribed 2 times a day
Group 1	platelet rich fibrin	platelet rich fibrin placed into the socket of the extraciton tooth + Augmentin 1gr tablet prescribed 2 times a day
Group 1	Diagnoses	platelet rich fibrin placed into the socket of the extraciton tooth + Augmentin 1gr tablet prescribed 2 times a day
Group 3	traditional osteotomies	Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 2	Diagnoses	platelet rich fibrin placed in to the socket of the extractraciton tooth combined with low laser treatment extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 3	Analgesic	Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 1	Analgesic	platelet rich fibrin placed into the socket of the extraciton tooth + Augmentin 1gr tablet prescribed 2 times a day
Group 2	platelet rich fibrin	platelet rich fibrin placed in to the socket of the extractraciton tooth combined with low laser treatment extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 2	Antibiotics, Penicillin	platelet rich fibrin placed in to the socket of the extractraciton tooth combined with low laser treatment extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 2	low laser therapy, bicure laser	platelet rich fibrin placed in to the socket of the extractraciton tooth combined with low laser treatment extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Group 3	Antibiotics, Penicillin	Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Control group.	Antibiotics, Penicillin	Tradional osteomy was made. + Augmentin 1gr tablet prescribed 2 times a day
Control group.	Analgesic	Tradional osteomy was made. + Augmentin 1gr tablet prescribed 2 times a day
Group 3	low laser therapy, bicure laser	Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day
Control group.	traditional osteotomies	Tradional osteomy was made. + Augmentin 1gr tablet prescribed 2 times a day

Primary Outcome Measures

Name	Time	Method
Swelling	Day 7	measured using a flexible plastic measuring tape as described by Gabka and Matsumura by measuring the distance from the corner of the mouth to the attachment of the earlobe following the bulge of the cheek and the distance from the outer canthus of the eye to the angle of the mandible.
Visual analogue scale (VAS)	Day 7	It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured.
Trismus	Day 7	Trismus by measuring the distance between the mesial incisal corners of the upper and lower right incisors during maximum mouth opening.

Secondary Outcome Measures

Name	Time	Method
the number of analgesic tablets	Day 7

Trial Locations

Locations (1)

Near East University; 🇨🇾 Nicosia, Lefkosa, Cyprus