Microbiological Examination of Children Operated for Congenital Lacrimal Stenosis

• Conditions: Congenital Lacrimal Stenosis

• Registration Number: NCT00312689
• Lead Sponsor: University Hospital Muenster

Brief Summary

Children with congenital lacrimal stenosis are treated by probing and intubation of the lacrimal drainage system.

Hypothesis: Microbiological findings at the time of insertion and removal of the silicon intubation have an influence on the clinical outcome and success rate of the surgical treatment. Microbiological specimens are taken from conjunctiva and nasal mucosa during the two procedures under general anaesthesia and from the silicon tube after removal and examined for bacterial contamination.

Detailed Description

Children (age 0-14 years) with congenital lacrimal stenosis in whom probing and intubation of the lacrimal drainage system is indicated are included the study after informed written consent by their parents. Microbiological specimens are taken bilaterally from conjunctiva and nasal mucosa during the two procedures under general anaesthesia (insertion and removal of the silicon intubation) and from the silicon tube after removal. Specimens are examined for bacterial contamination. Microbiological findings are correlated with clinical data about the further clinical course and especially the success of the surgical treatment.

Study Timeline

• Study Start: 2006-03
• Study First Submitted: 2006-04-07
• Study First Submitted QC: 2006-04-07
• Study First Posted: 2006-04-10
• Status Verified: 2007-04
• Study Completion: 2007-04
• Last Update Submitted: 2007-04-11
• Last Update Posted: 2007-04-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

age 0-14 years, congenital lacrimal stenosis, informed consent by the parents -

Exclusion Criteria

none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Augenklinik; 🇩🇪 Muenster, Germany