Comparison of the therapeutic benefit to combination therapy of botulinum neurotoxin and cast as well as single dose of botulinum neurotoxin on the wrist spasticity in different time intervals

eurologisches Rehabilitationszentrum Leipzig0 个研究点目标入组 60 人开始时间: 2016年6月7日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Aged 18 years - stoke with spasticity of the upper limb -MAS 2 - 3 - noticeable catch (according to Tardieu Scale) -pROM wrist affected: = 0 ° in extension

•- Age <18 years - MAS = 1+ or> 3 - wrist is not up to the 0 position (PROM) mobilized - no meaningful catch (Tardieu Scale) - fixed contracture of the fingers and / or wrist - Serious additional diseases - severe communication disorder - myasthenia gravis, Lambert-Eaton syndrome, ALS or other serious neuromuscular diseases - severe dysphagia - current administration of aminoglycosides - proven hypersensitivity to Clostridium botulinum toxin A or any of the excipients of the preparation Dysport® - Planned operations within the next 12 weeks ago - pregnancy, lactation period - anticoagulant therapy (Warfarin, Falithrom) - infections in the injection area and skin damage in the area of ??castings - Significant edematous swelling of the arm and hand - Peri-articular heterotrophic ossification in the investigation area - Unstable fractures in the study area - gout and diseases of rheumatic at the involved joints (upper limb)

发起方

eurologisches Rehabilitationszentrum Leipzig