Attentional Capture by Real-life Episodic Information
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 86
- 试验地点
- 1
- 主要终点
- activation pattern in fMRI: "old vs. new" objects (intervention 1)
研究概览
简要总结
Attention facilitates the allocation of processing resources and the control of behavior among competing stimuli. Current research focuses primarily on attention control networks in the dorsal frontoparietal (DAN) and ventral (VAN) cortex. However, typical laboratory experiments emphasize task-specific processing, neglecting the possible role of memory. Although a few studies have examined the contribution of memory to attention control, they have generally used simple tasks in the laboratory. These tasks are unlikely to produce true traces of episodic memory, which are - by definition - characterized by complex contextual information (what, where, when) and personal relevance. This research will therefore use an innovative protocol based on mobile phone technology to generate episodes in the participants' real lives and then measure the impact of these past personal experiences on attention allocation (by assessing eye movements) and on the activity of the DAN/VAN system (using functional imaging).
The main hypothesis of the study is that knowledge acquired during everyday life contributes to the subsequent allocation of processing resources, via engagement of the DAN/VAN attention systems.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Be 18 years old to 40 years old
- •Be right-handed
- •Do not wear glasses
- •Have a mobile-phone compatible with the application, minimum 6rd generation Android operating system, with geo-localization activated and accepted by the user
- •Undertake to comply with the instructions and recommendations for MRI examination
- •Provide informed written consent to participate in the study
排除标准
- •History of known neurological or psychiatric illness
- •Cognitive problems limiting the understanding of instructions
- •Recent taking psychotropic drugs (antidepressants, anxiolytics, antipsychotics). The main treatments not authorized during this research are the following: Psychotropic treatments (drugs that can induce changes in perception, sensation, mood, consciousness or behavior). Like what:
- •Antipsychotics (valproic acid, amisulpride, aripiprazole, clozapine, cyamemazin, haloperidol, loxapine, olanzapine, risperidone).
- •Antidepressants (Amitriptyline, Citalopram, Clomipramine, Duloxetine, Escitalopam, Fluoxetine, Mianserine, Mirtazapine, Nortriptyline, Paroxetine, Sertraline, Venlafaxine).
- •Anxyolitics
- •Pregnant or breastfeeding women
- •Persons deprived of their liberty by a judicial or administrative decision
- •Persons admitted to a health or social institution for purposes other than research
- •Adults subject to a legal protection measure (guardianship, curatorship)
- •Persons not affiliated to a social security scheme or beneficiaries of a similar scheme
- •Participation in another research study of the current study
- •Contraindication for fMRI scanning
- •Participant not agreeing to be informed in the event of the incidental discovery of an anomaly on MRI
- •For visit number 2 :
- •Alcohol consumption (> 3 drinks) in the 24h before the experiment
- •Alcohol consumption the day of the experiment
- •Cafeine consumption 1 hour or less before the experiment
- •Drug consumption within the 24h preceding the experiment
- •Antimalarial treatment within the 3 days preceding the experiment
研究组 & 干预措施
Old vs new objects
The following week after the "Old vs new objects" encoding phase of 3 weeks, participants will have an fMRI.
During fMRI, participants will see objects already seen or not seen during the encoding phase.
干预措施: Old vs new objects" encoding phase and fMRI (Behavioral)
incongruent vs. congruent contexts
The following week after the "incongruent vs. congruent contexts" encoding phase of 3 weeks, participants will have an fMRI.
During fMRI, participants will see objects encoding in congruent or incongruent contexts.
干预措施: " incongruent vs. congruent contexts " encoding phase and fMRI (Behavioral)
结局指标
主要结局
activation pattern in fMRI: "old vs. new" objects (intervention 1)
时间窗: One time during the week after the 3 weeks encoding phase
activation pattern in DAN/VAN system in fMRI experiments for the comparison of trials with gaze directed towards "seen/old vs. unseen/new" objects.
次要结局
- activation pattern in fMRI: "place" images in intervention 1(One time during the week after the 3 weeks encoding phase)
- activation pattern in fMRI: incongruent vs. congruent contexts (intervention 2)(One time during the week after the 3 weeks encoding phase)