The Clinical and Virology effects of NA inhibitor in influenza virus infections (age;over 4 years old, under 13 years old):an open-label,randomized study Part 2.
Not Applicable
- Conditions
- Childfood influenza infections
- Registration Number
- JPRN-UMIN000012670
- Lead Sponsor
- Hirotsu Clinic
- Brief Summary
1st half of the study result (virus dynamics)were shown below: http://www.tandfonline.com/doi/pdf/10.1080/14787210.2018.1421945?needAccess=true 2nd half of the study result (antibody dynamics) has been submitted (under review)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 160
Inclusion Criteria
Not provided
Exclusion Criteria
1)History of hypersensitivity caused by neuraminidase inhibitors. 2)Patients with (high risk factors) underlying disease that is estimated to affect the course of virus. 3)Patients were deemed inappropriate for the study participants.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Time to virus disappeared from the start of drug administration
- Secondary Outcome Measures
Name Time Method -Time to return to normal body temperature (under 37.5 degrees) -Time of flu symptoms to disappear -The amount of change per unit time of the virus titer to the last observation time and day 3 -The drug sensitivity change for each NA inhibitor -The time course and antibody titer -Rate of relapse