A study to assess the efficacy of Dexamethasone as an adjuvant in ultrasound guided cervical plexus block using Bupivacaine 0.25% in patients undergoing thyroid surgery under general anesthesia

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2021/04/032612
• Lead Sponsor: Dr Archana M

Brief Summary

This is a prospective randomised control trial to study the effect of dexamethasone as an adjuvant with bupivacaine 0.25% versus Bupivacaine 0.25% alone using ultrasound guided superficial cervical plexus block  in patients undergoing thyroid surgeries under entropy guided general Anesthesia of duration less than 2 hours 30mins. It will be conducted in a total of 80patients, 40 in each group in all hospitals attached to Bangalore medical college and research institute. The primary outcome is to compare hemodynamic variables intraoperatively. Isoflurane consumptions, entropy intraoperatively and postop analgesia and side effects will be observed in the post operative period

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-06-04
• Study Start: 2021-12-04

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients who have given informed written consent 2.
• Patients with ASA grade 1 and 2 3.
• Patients ages 18-60years of either sex 4.
• Patients scheduled for elective thyroid surgeries lasting for 60 to 150 minutes.

Exclusion Criteria

• Patients not willing to give informed consent 2.
• Patients with allergy to Bupivacaine 3.
• Patients diagnosed with vocal cord palsy by preoperative indirect laryngoscopes 4.
• Patients with thyroid mass extending retrosternalily, any gross compression or deviation of trachea 5.
• Patients scheduled for extensive radical neck dissection 6.
• Patients with electrolyte abnormalities, hepatic or renal insufficiency, coagulation disorder, hypertension or cardiac disorders 7.
• Pregnant and breast feeding women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hemodynamic stability	Hemodynamic stability

Secondary Outcome Measures

Name	Time	Method
Isoflurane consumption	Intraoperative period
Other adverse effects	Post operative period
Analgesia	Post operative period

Trial Locations

Locations (1)

Bangalore medical college and research institute; 🇮🇳 Bangalore, KARNATAKA, India

Bangalore medical college and research institute

🇮🇳Bangalore, KARNATAKA, India

Dr Archana M

Principal investigator

9663310314

archanamanoharan25@gmail.com