Hypoalgesic Effect of Cervical Manipulation

Not Applicable

Completed

• Conditions: Pain
• Interventions: Device: Global manipulation; Device: Especific manipulation

• Registration Number: NCT03541538
• Lead Sponsor: Universidade Federal de Sao Carlos

Brief Summary

This study evaluates the hypoalgesic effect of global and specific cervical joint manipulation in healthy individuals. At first the participants received one of the interventions and after 48 hours, the other.

Detailed Description

Cervical Joint Manipulation (CJM) are often used for pain treatment.

Joint manipulation generates a series of stimuli within the central nervous system through the activation of proprioceptors located in the joint capsule or muscles, stimulates the PAG, causing pain inhibition by activation of non-opioid descending inhibitory pathways.

Study Timeline

• Study First Submitted: 2018-05-17
• Study First Submitted QC: 2018-05-17
• Study First Posted: 2018-05-30
• Study Start: 2018-06-20
• Primary Completion: 2018-06-20
• Study Completion: 2018-07-20
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-11
• Last Update Posted: 2020-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• healthy subjects of both sexes
• without pain complaints in the last 90 days

Exclusion Criteria

• previous spinal surgeries
• spinal canal stenosis
• vertebral fracture
• spondylolisthesis
• cancer
• acute infections
• hemorrhagic disorders
• active tuberculosis
• deep vein thrombosis
• osteoporosis
• rheumatic diseases
• metabolic diseases
• cardiorespiratory diseases
• smoking injury
• musculoskeletal injury
• use of pacemaker
• women in menstrual period
• pregnant women
• use of pain-killers in the last 48 hours
• use of anti-inflammatory drugs in the last 48 hours
• previous joint manipulation treatments
• aversion to cervical joint manipulation
• positivity in the vertebral artery test
• headache in the last seven days

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Global manipulation	Global manipulation	Manual therapy performed in the cervical region in a non-specific way.
Especific manipulation	Especific manipulation	manual therapy performed specifically on the C6-7 segment

Primary Outcome Measures

Name	Time	Method
Pressure Pain Threshold at the posterior region of the forearm	1 minute after the end of the intervention.	The subjects were placed supine on a stretcher with their elbows fully extended and the anterior portion of the forearm resting on the stretcher. Subjects were instructed to keep their eyes closed during attempts. The examiner used a Somedic Type II digital pressure algometer (Somedic Inc, Hörby, Sweden) on the posterior region of the forearm 10cm below the lateral epicondyle of the elbow towards the third finger, keeping the forearm in pronation. The pressure was then applied perpendicular to the skin at a rate of 40kPa / s using a 1cm2 flat circular probe covered with 1mm of rubber to prevent any skin pain caused by sharp metal edges.

Trial Locations

Locations (1)

Ufscar - Universidade Federal de São Carlos; 🇧🇷 São Carlos, São Paulo, Brazil