Time of Exercise Re-training With Chronic Obstructive Pulmonary Disease (COPD)

Not Applicable

Recruiting

• Conditions: Respiratory Diseases
• Interventions: Other: Pulmonary rehabilitation

• Registration Number: NCT06366113
• Lead Sponsor: Michaël RACODON

Brief Summary

Pulmonary rehabilitation (PR) is an effective intervention for reducing hospital readmissions, secondary events, and mortality in patients with respiratory pathologies.

The program should not be improved by introducing new subjects such as circadian rhythm.

Detailed Description

Respiratory diseases are a leading cause of death in developed countries. To avoid complications and recurrences, secondary prevention in patients with respiratory diseases is essential. Pulmonary rehabilitation (PR) is a well-established and effective treatment that is supervised by medical professionals and conducted in dedicated centres. It has been shown to reduce hospital readmissions, secondary events, and patient mortality.

The timing of reconditioning is crucial. Previous studies have indicated that training times affect strength and power gains. Additionally, the time of day for training can significantly impact progress in aerobic capacity.

Disturbances to the biological clock can have consequences for people with respiratory pathologies, particularly an alteration in muscular function.

Therefore, studying the temporal specificity of exercise re-training in patients with respiratory diseases is of interest.

Study Timeline

• Study Start: 2024-01-02
• Primary Completion: 2024-01-02
• Status Verified: 2024-04
• Study First Submitted: 2024-04-10
• Study First Submitted QC: 2024-04-10
• Study First Posted: 2024-04-15
• Last Update Submitted: 2024-08-19
• Last Update Posted: 2024-08-20
• Study Completion: 2026-07-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Age ≥ 18 years
• Patient with chronic obstructive pulmonary disease (COPD)
• Registered for respiratory re-education and rehabilitation at the Clinique de la Mitterie
• Number of rehabilitation sessions at least 18 over 4 weeks
• Written informed consent signed by the patient
• Membership of a social security

Exclusion Criteria

• • cardiovascular contraindications to exercise
• unstable respiratory status (uncompensated respiratory acidosis)
• conditions interfering with the pulmonary rehabilitation process (progressive neuromuscular disease, psychiatric illness)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Afternoon group	Pulmonary rehabilitation	Endurance and muscular exercise can be performed in the afternoon, from 3:00 pm to 3:45 pm, or vice versa.
Morning group	Pulmonary rehabilitation	Endurance and muscular exercise can be performed in the morning, either at 9:00am or 9:45am, or vice versa.

Primary Outcome Measures

Name	Time	Method
6-minute walk test (6MWT)	15 minutes	Walking distance in a test

Secondary Outcome Measures

Name	Time	Method
Time limit test (Time-lim)	0 to 900 secondes	Endurance exercise holding time in seconds
Sit to stand test (STT)	1 minute	The number of sit-to-stand repetitions during the test.
Single arm curl Test (SAC)	1 minute	The number of bends during the test
Pittsburgh Sleep Quality Index	10 minutes. The total score ranges from 0 to 21, with 0 indicating no difficulties and 21 indicating major difficulties.	Sleep quality score
Single-leg stance test (SLT)	1 minute	The time for balance
Hospital Anxiety and Depression Scale (HAD)	10 minutes. The maximum mark for each score is 21 and the minimum mark is 0. The higher the score, the more depressed or anxious the person.	Hospital Anxiety and Depression score

Trial Locations

Locations (1)

Clinique la Mitterie; 🇫🇷 Lille, France