跳至主要内容
临床试验/CTRI/2021/01/030269
CTRI/2021/01/030269已完成不适用

A Study To Evaluate The Efficacy Of Patu Vyoshadi Sukhambu Nasya and Vyaghradi Kashaya in Kaphaja Prathishyaya

DR HARIKRISHNAN N MENON1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2021年7月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
1) ABSOLUTE EOSINOPHIL COUNT (AEC)400cells/µL

研究概览

简要总结

Prathishyaya is one among thecommon diseases affecting respiratory system. Kaphaja prathishyaya is characterised by snigdha Shukla kapha sruthi, Kandu in nasa thalu gala,  shiro guruthva, shoonakshi, kasa.

Based on  above symptoms it can becompared with Allergic Rhinitis (ICD-J30.2,J30.89).It is adisorder of nose induced by an IgE mediated inflammation afterAllergen exposure leading to Rhinorrhea, nasal pruritus, bilateral nasalstuffiness associated with cough, chest tightness. Worldwide iteffects between 10-25%  of thepopulation. In Indiait constitutesmore than 50% of all allergies, 20-30%people  suffer from it, andare prone to bronchial asthma in later stage.

In conventional medicinal system it is treated with antihistamines, nasaldecongestants, corticosteroids, topical steroids which causes different sideeffects like drowsiness, rhinitis medicamentosa, mucosal atrophy, severalsystemic disorders etc.By considering these facts there is a need todevelop a treatment which aims at reducing symptoms and improving immunity toovercome this condition.

Nasya is a line of treatment for most ofthe urdhwa jatru vikaras. In kaphaja prathishyaya, nasya with theekshna dravyas can give positive results hencePatu vyoshadi sukhambu nasya  is taken. It can improve nasal mucosa functionby direct cleansing, removal of inflammatory mediators and enhancingmucociliary function.  VyaghradiKashaya is taken,as the drugsmentioned in this yoga is theekshna,ushna and rooksha which act askapha hara. They are also costeffective and easily available.Considering above facts these yoga’s are expected to yield betterresults, hence the present study has been taken.

HYPOTHESIS

NULL HYPOTHESIS:

H0: There is no effectof patu vyoshadi sukhambu  nasya and Vyaghradi Kashaya  internally in kaphaja prathishyaya

ALTERNATEHYPOTHESIS**:**

H1: There is asignificant effect of Patu vyoshadisukhambu nasya and Vyaghradi Kashaya internallyin kaphaja prathishyaya.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • ALLERGIC RHINITIS UNSPECIFIED.

排除标准

  • 1.SUBJECTS CONTRAINDICATED FOR NASYAKARMA
  • SUBJECTS SUFFERING FROM OTHER SYSTEMIC AND INFECTIOUS DISEASE LIKE UNCONTROLLED DIABETES, HTN, TB, HIV SHALL BE EXCLUDED
  • SUBJECTS SUFFERING WITH POLYPS, DNS REQUIRING SURGICAL INTERVENTION
  • PREGNANT AND LACTATING WOMEN.

结局指标

主要结局

1) ABSOLUTE EOSINOPHIL COUNT (AEC)400cells/µL

时间窗: 58 DAYS

2) ERYTHROCYTE SEDIMENTATION RATE (ESR)20mm/hr

时间窗: 58 DAYS

次要结局

  • ASSESSED USING ‘TOTAL NASAL SYMPTOM SCORE’(1) NASAL DISCHARGE)

研究者

发起方
DR HARIKRISHNAN N MENON
申办方类型
Other [self]

研究点 (1)

Loading locations...

相似试验