ACTRN12614000092695已完成4 期
A randomised double-blind controlled trial of lignocaine/phenylephrine nasal spray vs placebo for pain and distress of nasogastric tube insertion in children
Dr Simon Craig0 个研究点目标入组 100 人开始时间: 2014年1月23日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 6 Months 至 5 Years（—）
- 性别
- All
入选标准
- •Children who are (1) aged 6 months to 5 years of age AND (2) weigh at least 6kg who are due to have a nasogastric tube inserted as part of their emergency department treatment.
排除标准
- •*Inability to gain informed consent from parent or guardian
- •*Indication for an urgent insertion of a nasogastric tube
- •*Accompanying adult is non-English speaking and no interpreter service is available
- •*Child or parent has an allergy to lignocaine or phenylephrine
- •*Aberrant nasal anatomy
- •*Acute or chronic nasal problems or nasal trauma that may preclude adequate administration or absorption of intranasal medication.
- •*Cardiovascular disease / congenital heart disease – specifically hypertension, severe bradycardia, conduction disturbances and digitalis intoxication
- •*Known hepatic or renal impairment
- •*Asthma (particularly sulfite-sensitive asthma)
- •*Genetic predisposition to malignant hyperthermiaPre-existing abnormal neurological conditions
- •*Child is taking medications known to interact with Co-phenylcaine Forte (Antiarrhythmic drugs;Suxamethonium; Phenytoin;Antidepressants; Propranolol;)Citicoline
研究者
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