Venous Site for Central Catheterization

Not Applicable

Completed

• Conditions: Catheterization; ICU; Critical Care
• Interventions: Procedure: Randomization of the site for catheterization

• Registration Number: NCT01479153
• Lead Sponsor: University Hospital, Caen

Brief Summary

Central venous catheters are needed in the critical care setting to administer drugs. Three sites are available to gain vascular access: subclavian, internal jugular and femoral. Each site has complications, but there is no randomized controlled study which compared the 3 sites.

The investigators hypothesis is that subclavian catheterization reduces the risk of major complications compared to internal jugular or femoral.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-10
• Study First Submitted: 2011-11-22
• Study First Submitted QC: 2011-11-23
• Study First Posted: 2011-11-24
• Primary Completion: 2014-11
• Study Completion: 2015-02
• Status Verified: 2015-07
• Last Update Submitted: 2016-08-22
• Last Update Posted: 2016-08-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3471

Inclusion Criteria

• Patient admitted in the Intensive Care Unit
• Requiring Central Venous Catheterization

Exclusion Criteria

• Patients with only one site available

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Femoral Catheterization	Randomization of the site for catheterization	-
Subclavian catheterization	Randomization of the site for catheterization	-
Internal Jugular catheterization	Randomization of the site for catheterization	-

Primary Outcome Measures

Name	Time	Method
Major complications including catheter-related bloodstream infection	From central catheter insertion to 48-h after removal	Catheter-related bloodstream infection: (positive catheter-tip quantitative culture plus positive peripheral blood culture(s))

Trial Locations

Locations (5)

Polyvalent Intensive Care Unit, Mémorial France Etats-Unis; 🇫🇷 Saint Lô, France

Medical Intensive Care Unit, CHU Caen; 🇫🇷 Caen, France

Surgical Intensive Care Unit, CHU Caen; 🇫🇷 Caen, France

Medical Intensive Care Unit, Cochin, AP-HP; 🇫🇷 Paris, France

Médical Intensive Care Unit, Lariboisière, AP-HP; 🇫🇷 Paris, France