NCT00312351终止4 期
An Exploratory Randomized, Double-Masked, Multi-Center Comparative Trial, in Parallel Groups, to Explore the Safety and Efficacy of Three Different Doses of Intravitreous Injections of Pegaptanib Sodium (Anti-VEGF Pegylated Aptamer) Given Every 6 Weeks for 102 Weeks, in Patients With Subfoveal Neovascular Age-Related Macular Degeneration (AMD)
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 262
- 试验地点
- 2
研究概览
简要总结
The purpose of this trial is to compare the ability of three different doses of pegaptanib sodium to safely and effectively minimize fluid leakage within the eye, thereby stabilizing or improving vision in patients with wet AMD. The study will also examine the effects of pegaptanib sodium on the cornea and sensory retina of patients with wet AMD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects of either gender, aged 50 years or greater.
- •Subfoveal choroidal neovascularization (CNV) due to AMD.
- •Best corrected visual acuity in the study eye between 20/40 and 20/
- •Normal electroretinogram, and corneal endothelial cell density of 1500 cells/mm2 or more.
排除标准
- •Any prior photodynamic therapy (PDT) with Visudyne or thermal laser to the study eye.
研究者
研究点 (2)
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