EUCTR2016-004755-75-FR进行中（未招募）1 期
Intra articular injection of microfat and platelet-rich plasma in the treatment of knee osteoarthritis : a pilot study - MICROPREP
Clinique Juge0 个研究点目标入组 30 人开始时间: 2017年2月20日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •1. Males and females between 20 to 65 years of age
- •2. Symptomatic knee osteoarthritis , ICRS grade 2, 3 ou 4
- •3. BMI between 20 to 30
- •4. Written informed consent, signed by patient or legal representative
- •(if patient unable to sign).
- •5.HB > 10g/dl
- •6.Negative pregnancy test
- •7.Social security affiliated
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 30
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range 0
排除标准
- •1.IRM contre-indications: ocular loose bodies, pace maker, neurostimulateur, cochlear implant, vascular clips, mettalic cardiac valve
- •2.BMI < 20
- •3.Thrombocytopenia < 150 G/L
- •4.Thrombocytosis > 450 G/L
- •5.Thrombopathy
- •6.TP < 70%
- •7.TCA patient / witness rapport > 1,20
- •8.Anaemia: HB < 10g/dl
- •9. Positive serology VIH1 and 2, Agp24, Ac HCV, Ag HbS, AcHbc, Ac HTLV I and II, TPHA
- •10.Treatment by platelet inhibiting agent, aspirin, anti vitamin K completed more than 2 weeks before inclusion
- •11.Chronic treatment by corticosteroid per os or treatment completed more than 2 weeks before inclusion
- •12.Intra articular knee injection of corticosteroid more than 8 weeks before inclusion
- •13.Intra articular knee injection of hyaluronic acid more than 8 weeks before inclusion
- •14.NSAI treatment completed more than 2 weeks before inclusion
- •15.Fever or recent disease
- •16.Auto immune disease
- •17.Inflammatory Arthritis
- •18.Immune deficit
- •19.Infectious disease
- •20.Malignant tumor being treated or history of malignant tumor
研究者
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