Agitation, aggression and arrousal in patients suffering from psychosis - comparison parenteral benperidol, ziprasidone and aripiprazole

• Conditions: F25; F20; Schizophrenia; Schizoaffective disorders

• Registration Number: DRKS00004620
• Lead Sponsor: VR-Klinik Köln

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01-21
• Study Completion: 2019-08-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

diagnosis (ICD10) of schizophrenia (F20) or schizoaffective disorder (F25)

BPRS of at least 12 points
age of 18 up to 65 years
written informed consent on participation to the study

Exclusion Criteria

Patients which do not fullfill the criteria (ICD10) for schizophrenia or schizoaffective disorder.
Age under 18 or over 65 years.
A BPRS of lower then 12 points.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Change of BPRS<br>2. Change of positive and negative syndrome scale - excited component

Secondary Outcome Measures

Name	Time	Method
1. total number of parenteral injections<br>2. duration of parenteral incejtions in days<br>3. duration of treatment in hospital after last parenteral injection<br>4. dose of sedatives given to patients in chlorpromazin equivalents<br>5. side effects and acceptance rated by UKU Rating Scale<br>6. acceptance of patients the day after the last injection by visual analog scale