CTRI/2020/02/023092
Not yet recruiting
未知
Identifying association of gene polymorphism and Prakriti in responders and non responders to dual antiplatelet therapy in coronary artery disease patients
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: I22- Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
- Sponsor
- A
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. North Indian ethnicity
- •2\. CAD patients (stable angina, non ST elevation and ST elevation myocardial infarction) presenting to Cardiology OPD, AIIMS after 30days of PCI up to 180 days
- •3\. Patients receiving dual antiplatelet therapy and on stable dose of clopidogrel upto 150 mg once a day and aspirin upto 150 mg once a day for a minimum period of 30 days
- •4\. Willing to participate in the study
Exclusion Criteria
- •1\. Patients under anti coagulation therapy
- •2\. Use of intensified antiplateletagents other than standard dual antiplatelet therapy
- •3\. h/o Bleeding disorders (Hemophilia, von Willebrand disease), hospitalization related to bleeding
- •4\. Chronic kidney disease (eGFR \< 60 ml/min)
- •5\. Any contraindications if elicited to antiplatelet therapy
- •6\. Patients with hemoglobin \< 10
- •7\. Patients with platelet count \< 100K
- •8\. Patients with major surgery within 1 week
- •9\. Patients with regular need of NSAID or prednisone(not taken in past 2 weeks)
- •10\. Females with pregnancy or lactation
Outcomes
Primary Outcomes
Not specified
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