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EUS-FNB for AIP Study

Not Applicable
Conditions
Autoimmune pancreatitis
Registration Number
JPRN-jRCTs042180092
Lead Sponsor
Ishikawa Takuya
Brief Summary

EUS-FNB with a 22-gauge Franseen needle demonstrated favorable detection rates which would be clinically beneficial for the histological diagnosis of autoimmune pancreatitis.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
56
Inclusion Criteria

1)Patients who meet image criteria of autoimmune pancreatitis (AIP) on International consensus diagnostic criteria (ICDC) and have not treated before.
2)Patients between 20 and 85 years old at the time of enrollment.
3)Performance status of 0 to 1.
4)Preservation of main organ functions at the time of diagnosis.
5)Provision of written consent to participate in the study.

Exclusion Criteria

1)Steroid administration within 3 months before the initiation of treatment.
2)Poorly controlled infection (including active tuberculosis).
3)Serious drug allergy.
4)Difficult in observation of the course of endoscopy.
5)Malignant tumor.
6)Serious adverse events.
7)Pregnant and lactating women, women who are possibly pregnant, and women who might want to become pregnant.
8)Severe mental disorder
9)Judgement as being ineligible by the principal or subinvestigator.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Detection rate of pathological findings with meet level 1 of International consensus diagnostic criteria for autoimmune pancreatitis by EUS-FNB
Secondary Outcome Measures
NameTimeMethod
1)Detection rate of pathological findings which meet level 2 of International consensus diagnostic criteria (ICDC) by EUS-FNB<br>2)Detection rate of each pathological finding in ICDC by EUS-FNB<br>3)Contribution degree of EUS-FNB in the diagnosis of autoimmune pancreatitis<br>4)Complications of EUS-FNB
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