Geometric accuracy of accelerated partial breast irradiation on the Cyberknife using standard surgical clips as a fiducial marker
- Conditions
- breast cancerbreast carcinoma1000629110006295
- Registration Number
- NL-OMON48772
- Lead Sponsor
- Radiotherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 51
- Female
- Age * 50 years
- Stage pTis, pT1 or pT2 (tumor size < 3 cm) breast cancer
- Invasive ductal, mucinous, tubular, medullary or colloid carcinoma or DCIS
- Treated with breast-conserving surgery
- Resection margins negative at ink for invasive cancer and by * 2mm for DCIS
- ER positive
- pN0 confirmed by sentinel node biopsy or axillary lymph node dissection. If the risk of regional metastasis is deemed so low that a sentinel node is not indicated (for example in DCIS), cN0 is sufficient and patients are eligible for trial participation without sentinel node biopsy.
- At least 3 surgical clips in the tumor bed, being large titanium (1 cm) or tantalum type
- Lympho-vascular infiltration
- Extensive intraductal component
- Multifocal or multicentric disease
- Invasive lobular carcinoma
- Distant metastasis
- Neoadjuvant chemotherapy
- Prior irradiation to the chest
- Inability to read Dutch
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study endpoint is to report the geometric uncertainty of CK-APBI in<br /><br>order to calculate the required PTV margin.</p><br>
- Secondary Outcome Measures
Name Time Method