Innovative methods for early detection and interpretation of chemical exposure using human biological monitoring.
- Conditions
- Toekomstige beroepsziektenOccupational diseases
- Registration Number
- NL-OMON56958
- Lead Sponsor
- niversiteit Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 400
Inclusion Criteria
It concerns a population eligible for a periodic occupational health
examination (PAGO) that the employer must offer to its employees according to
Article 18 of the Occupational Health and Safety Act.
Exclusion Criteria
In this study, no exclusion criteria are applied.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameters encompass data regarding metabolome including<br /><br>endogenous metabolites (amino acids, organic acids, nucleic acids, fatty acids,<br /><br>amine, sugars, vitamins, pigments, antibiotics, etc.) as well as exogenous<br /><br>chemicals (e.g., pharmaceuticals, pesticides, plasticizers, flame retardants,<br /><br>preservatives, and microbial metabolites) derived from blood samples. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Not secondary study parameters will be involved in this study. However, other<br /><br>parameters which are considered:<br /><br>- Food and drink consumption in the last year<br /><br>- Lifestyle and alcohol consumption<br /><br>- General health status and occurence of health outcomes</p><br>