The Effects of High-intensity Interval Training on Selected Steroid Hormones and Psychological Features in Healthy Male Adolescents: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Testosterone
研究概览
简要总结
The purpose of study was to investigate the effect of a high-intensity interval training (HIIT) intervention on cardiorespiratory fitness (CRF), hormonal, and mental health markers in male adolescents. The main question it aims to answer is: Does HIIT improve CRF, hormonal (testosterone and cortisol levels, testosterone:cortisol ratio), and mental health (depression, anxiety and stress scores) markers. Researchers will compare HIIT (designed to experimental group) to non-training intervention (designed to control group) to see if the training program works to improve the health status. HIIT consisted of three sessions per week for 10 weeks, comprising of three sets of four to eight bouts of 30-s runs at high intensity [100-110% of maximal aerobic speed (MAS)], interspersed with 30-s recovery runs at low intensity (50% of MAS) between bouts.
详细描述
High-intensity interval training (HIIT) is a time-efficient method for improving physical fitness in youth. However, limited evidence exists regarding its effects on testosterone and cortisol levels, testosterone:cortisol ratio, and mental health outcomes during adolescence, a critical period of development. This study was to investigate the effect of a HIIT intervention on cardiorespiratory fitness (CRF, expressed as maximal aerobic speed and maximal oxygen consumption), hormonal, and mental health markers in male adolescents. Twenty-eight healthy male adolescents (age, 14.9±0.74 yrs.) were randomized to a HIIT group (HIITG, n=15) or a non-training control group (CG, n=13). HIIT consisted of three sessions per week for 10 weeks, comprising of three sets of four to eight bouts of 30-s runs at high intensity [100-110% of maximal aerobic speed (MAS)], interspersed with 30-s recovery runs at low intensity (50% MAS) between bouts. Pre- and post-intervention assessments included CRF (VO2max), hormonal markers (testosterone, cortisol, and testosterone:cortisol ratio), and mental health markers (depression, anxiety and stress scores).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 16 Years（Child）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •male sex,
- •age 14 to 16 years,
- •normal weight according to the WHO child growth standards for BMI (BMI ≤ 85th percentile)
- •parental approval.
排除标准
- •medical conditions contraindicating intense physical exercise
- •non-compliance with the training program
- •habitual physical activity exceeding school physical education lessons
- •current or recent (within 3 months) dietary supplementation or restriction
- •incomplete data.
结局指标
主要结局
Testosterone
时间窗: One day before the start and two days after the completion of the 10 weeks of training program.
Testosterone concentration, expressed in nmol/L, was analyzed using enzyme-linked immunosorbent assay (ELISA) kits (Monobind, Inc., Lake Forest, CA).
Cortisol
时间窗: One day before the start and two days after the completion of the 10 weeks of training program.
Cortisol concentration, expressed in nmol/L, was analyzed using enzyme-linked immunosorbent assay (ELISA) kits (Monobind, Inc., Lake Forest, CA).
Depression, Anxiety, and Stress Scale - 21 items (DASS-21)
时间窗: Before the start and after the completion of the 10 weeks of training program.
The DASS-21 is a self-report questionnaire that assesses symptoms of depression, anxiety, and stress (Lai et al., 2015). Each item is scored from 0 to 3, yielding a total score ranging from 0 to 63. Higher scores indicate worse psychological symptoms (greater levels of depression, anxiety, or stress). In the present study, we used the Arabic version of the DASS-21, which has been validated and shown to have good psychometric properties (Moussa et al., 2017), to ensure linguistic and cultural appropriateness for assessing adolescents' psychological well-being.
The testosterone/cortisol ratio
时间窗: One day before the start and two days after the completion of the 10 weeks of training program.
The testosterone/cortisol ratio (T/C) was calculated by dividing the testosterone value by the cortisol value for each participant.
次要结局
- Maximal aerobic speed(Before and after the 10 weeks of the training program.)
- Maximal oxygen consumption(Before and after the 10 weeks of the training program.)
研究者
Nejmeddine Ouerghi
Principal Investigator
High Institute of Sports and Physical Education of Kef