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Clinical Trials/NCT02521350
NCT02521350
Unknown
Not Applicable

Perioperative Acute Kidney Injury Incidence and Risk Factors in Non-cardiac Surgery

Acibadem University0 sites5,000 target enrollmentJune 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Intensive Care Unit Syndrome
Sponsor
Acibadem University
Enrollment
5000
Primary Endpoint
Correlation with use of drugs before surgery and serum creatinine level at 24h after surgery
Last Updated
10 years ago

Overview

Brief Summary

In the last few years, acute renal injury (AKI) definition has been significantly changed. In the light of the data obtained from multicenter international studies, acute renal injury was redefined according to RIFLE, AKIN and KDIGO criteria. The common criteria of all three criteria in acute renal failure is the increment of level of creatinine as 0.3 mg/dL or 50 % increment of respective basal value of serum creatinine.

In the current study, older than 40 years patients with no specific gender, who will stay at least one night in hospital will be included and cardiovascular and urological surgery patients and patients with known renal insufficiency will be excluded. It was aimed to measure serum creatinine levels in all included patients at baseline and up to 24h after surgery and will be determined acute kidney injury incidence and risk factors according to new criteria.

Registry
clinicaltrials.gov
Start Date
June 2015
End Date
June 2016
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Acibadem University
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • older than 40 years
  • no gender specified
  • patients who will stay at least one night in hospital
  • patient with normal renal function

Exclusion Criteria

  • patient with renal dysfunction and cardiovascular, urological surgery patients

Outcomes

Primary Outcomes

Correlation with use of drugs before surgery and serum creatinine level at 24h after surgery

Time Frame: Use of drug before surgery and serum creatinine level at 24h after surgery will be correlated.

Change from baseline in serum creatinine levels at 24h after surgery

Time Frame: Serum creatinine levels will be measured at baseline and up to 24h after surgery

AKI incidence determination using 50 % or more than 0.3 mg/dL increment of creatinine levels

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