Perioperative Acute Kidney Injury Incidence and Risk Factors in Non-cardiac Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Intensive Care Unit Syndrome
- Sponsor
- Acibadem University
- Enrollment
- 5000
- Primary Endpoint
- Correlation with use of drugs before surgery and serum creatinine level at 24h after surgery
- Last Updated
- 10 years ago
Overview
Brief Summary
In the last few years, acute renal injury (AKI) definition has been significantly changed. In the light of the data obtained from multicenter international studies, acute renal injury was redefined according to RIFLE, AKIN and KDIGO criteria. The common criteria of all three criteria in acute renal failure is the increment of level of creatinine as 0.3 mg/dL or 50 % increment of respective basal value of serum creatinine.
In the current study, older than 40 years patients with no specific gender, who will stay at least one night in hospital will be included and cardiovascular and urological surgery patients and patients with known renal insufficiency will be excluded. It was aimed to measure serum creatinine levels in all included patients at baseline and up to 24h after surgery and will be determined acute kidney injury incidence and risk factors according to new criteria.
Investigators
Eligibility Criteria
Inclusion Criteria
- •older than 40 years
- •no gender specified
- •patients who will stay at least one night in hospital
- •patient with normal renal function
Exclusion Criteria
- •patient with renal dysfunction and cardiovascular, urological surgery patients
Outcomes
Primary Outcomes
Correlation with use of drugs before surgery and serum creatinine level at 24h after surgery
Time Frame: Use of drug before surgery and serum creatinine level at 24h after surgery will be correlated.
Change from baseline in serum creatinine levels at 24h after surgery
Time Frame: Serum creatinine levels will be measured at baseline and up to 24h after surgery
AKI incidence determination using 50 % or more than 0.3 mg/dL increment of creatinine levels