Perioperative Acute Kidney Injury Incidence and Risk Factors in Non-cardiac Surgery
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 5,000
- 主要终点
- Correlation with use of drugs before surgery and serum creatinine level at 24h after surgery
研究概览
简要总结
In the last few years, acute renal injury (AKI) definition has been significantly changed. In the light of the data obtained from multicenter international studies, acute renal injury was redefined according to RIFLE, AKIN and KDIGO criteria. The common criteria of all three criteria in acute renal failure is the increment of level of creatinine as 0.3 mg/dL or 50 % increment of respective basal value of serum creatinine.
In the current study, older than 40 years patients with no specific gender, who will stay at least one night in hospital will be included and cardiovascular and urological surgery patients and patients with known renal insufficiency will be excluded. It was aimed to measure serum creatinine levels in all included patients at baseline and up to 24h after surgery and will be determined acute kidney injury incidence and risk factors according to new criteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •older than 40 years
- •no gender specified
- •patients who will stay at least one night in hospital
- •patient with normal renal function
排除标准
- •patient with renal dysfunction and cardiovascular, urological surgery patients
结局指标
主要结局
Correlation with use of drugs before surgery and serum creatinine level at 24h after surgery
时间窗: Use of drug before surgery and serum creatinine level at 24h after surgery will be correlated.
Change from baseline in serum creatinine levels at 24h after surgery
时间窗: Serum creatinine levels will be measured at baseline and up to 24h after surgery
AKI incidence determination using 50 % or more than 0.3 mg/dL increment of creatinine levels
次要结局
未报告次要终点