MedPath

Determination of Perioperative Acute Kidney Injury Incidence

Conditions
Intensive Care Unit Syndrome
Registration Number
NCT02521350
Lead Sponsor
Acibadem University
Brief Summary

In the last few years, acute renal injury (AKI) definition has been significantly changed. In the light of the data obtained from multicenter international studies, acute renal injury was redefined according to RIFLE, AKIN and KDIGO criteria. The common criteria of all three criteria in acute renal failure is the increment of level of creatinine as 0.3 mg/dL or 50 % increment of respective basal value of serum creatinine.

In the current study, older than 40 years patients with no specific gender, who will stay at least one night in hospital will be included and cardiovascular and urological surgery patients and patients with known renal insufficiency will be excluded. It was aimed to measure serum creatinine levels in all included patients at baseline and up to 24h after surgery and will be determined acute kidney injury incidence and risk factors according to new criteria.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
5000
Inclusion Criteria
  • older than 40 years
  • no gender specified
  • patients who will stay at least one night in hospital
  • patient with normal renal function
Exclusion Criteria
  • patient with renal dysfunction and cardiovascular, urological surgery patients

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Correlation with use of drugs before surgery and serum creatinine level at 24h after surgeryUse of drug before surgery and serum creatinine level at 24h after surgery will be correlated.
Change from baseline in serum creatinine levels at 24h after surgerySerum creatinine levels will be measured at baseline and up to 24h after surgery

AKI incidence determination using 50 % or more than 0.3 mg/dL increment of creatinine levels

Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath