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Clinical Trials/NL-OMON53083
NL-OMON53083
Recruiting
Not Applicable

Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals. - DOLPHIN-GENESIS

Vrije Universiteit Medisch Centrum0 sites140 target enrollmentTBD
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Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Vrije Universiteit Medisch Centrum
Enrollment
140
Status
Recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Diagnosis of idiopathic PAH, according to ESC/ERS guidelines (ref: Galie ERJ
  • •Unaffected BMPR2 or other mutation carrier or other mutations associated with
  • •Healthy relative of heritable PAH patient not carrying the disease causing
  • •2\. Age \>18 and \<80 years
  • •3\. Able to understand and willing to sign the Informed Consent Form

Exclusion Criteria

  • •\- Pregnant subjects
  • •\- Claustrophobia
  • •\- Inability to provide informed consent
  • •\- In case of PAH patients: TLC \< 70%pred or radiographic evidence of
  • •interstitial lung disease
  • •\- In case of BMPR2 mutation carriers and family control subjects, one or more
  • •of the following: abnormal spirometry, TLC \< 70%, echocardiographic evidence of
  • •pulmonary hypertension

Outcomes

Primary Outcomes

Not specified

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