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Clinical Trials/NCT03052543
NCT03052543
Completed
Not Applicable

A Pilot Study to Determine the Outcomes of an Intraoperative Bispectral Index Monitor

Boston Children's Hospital1 site in 1 country60 target enrollmentMarch 7, 2018
ConditionsAnesthesia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anesthesia
Sponsor
Boston Children's Hospital
Enrollment
60
Locations
1
Primary Endpoint
BIS values
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This pilot study is being conducted to determine whether the intraoperative presence of a Bispectral Index Monitor (BIS), a non-invasive monitor, affects the perioperative and postoperative indices and outcomes. The BIS monitor is an adhesive sensor that is applied to the forehead to monitor EEG waves. This monitor is not a Standard of Care Monitor, yet in adult and pediatric studies it has been shown to decrease time to emergence, decrease volatile anesthesia requirement, decrease recovery time and in some cases, decrease post-operative morbidity (REFS). The effect on intra-operative and post-operative parameters, when BIS is present but not specifically designated to be used as a monitor to guide anesthesia delivery, has not been specifically examined. This will be the first pediatric study which applies BIS on all patients and randomizes the anesthesiologists to either be or not be privy to seeing the BIS values during intra-operative period.

Detailed Description

The BIS monitor is an adhesive sensor that is applied to the forehead to monitor EEG waves. In adult and pediatric studies, the BIS monitor has been shown to decrease time to emergence, decrease volatile anesthesia requirement, decrease recovery time and in some cases, decrease post-operative morbidity (REFS). The effect on intra-operative and post-operative parameters, when BIS is present but not specifically designated to be used as a monitor to guide anesthesia delivery, has not been specifically examined. This will be the first pediatric study which applies BIS on all patients and randomizes the anesthesiologists to either be or not be privy to seeing the BIS values during intra-operative period.

Registry
clinicaltrials.gov
Start Date
March 7, 2018
End Date
October 11, 2019
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Keira Mason

principal investigator

Boston Children's Hospital

Eligibility Criteria

Inclusion Criteria

  • orthopedic or urologic day surgery
  • 2 to 12 years old

Exclusion Criteria

  • anesthesiologist refusal
  • patient/parent refusal
  • allergy to the BIS adhesive
  • history of seizures

Outcomes

Primary Outcomes

BIS values

Time Frame: intraoperative period

Compare the BIS values in the BISblind and BISvisible groups

Secondary Outcomes

  • Amount of intravenous anesthetic medications administered(intraoperative period)
  • Pain scores(post operative period, until discharge from recovery room, assessed up to 10 hours)
  • Time to meet discharge criteria(post operative period, until discharge from recovery room, assessed up to 10 hours)
  • End tidal sevoflurane values(intraoperative period)
  • Agitation/delirium(post operative period, until discharge from recovery room, assessed up to 10 hours)

Study Sites (1)

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