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临床试验/NCT04231019
NCT04231019已完成不适用

"Knowledge, Awareness and Perception Regarding Molar-Incisor Hypomineralization Among General Dental Practitioners, Dental Specialists and Dental Students in Egypt"

Alaa Mohammed Yehia1 个研究点 分布在 1 个国家目标入组 800 人开始时间: 2018年9月16日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
800
试验地点
1
主要终点
knowledge of Egyptian dental practitioners regarding molar-incisor hypomineralization

研究概览

简要总结

Molar incisor hypomineralization (MIH) is one of the developmental enamel defect which is characterized by demarcated, qualitative defects of enamel of systemic origin affecting one to four first permanent molars (FPMs) and frequently associated with incisor involvement. Similar lesions can be seen in second primary molars and their presence has been reported as a predictive factor for developing MIH. Although the exact etiology of MIH is unclear, it is likely to be multi-factorial. Possible etiological factors of MIH are systemic conditions as pneumonia, upper respiratory tract infections, asthma, otitis media, hypoxia, high fever, hypocalcemia and exposure to antibiotics as amoxicillin.

The prevalence of MIH has been reported from several studies to be between 2.8 and 40.2 %, with the mean approximately 15 %. MIH is considered as a common clinical problem by several epidemiological studies from many countries.

Clinical presentation of MIH can include white, creamy and yellow-brown opacities, irregular areas of post eruptive breakdown, which can be mistaken diagnosed as hypoplasia or atypical caries. The condition is usually associated with a high disease burden, leading to pain, infection and tooth loss. Teeth affected by MIH are at high risk of rapid caries development and progression, rapid wear and enamel breakdown. Severely affected enamel disintegrates under masticatory forces resulting in post-eruptive breakdown (PEB), which is also a characteristic feature of MIH-affected teeth. These teeth require treatment, ranging from prevention to restorations and extractions, often under general anesthesia. A multidisciplinary cooperation among clinicians is often required, particularly for extractions of first permanent molars, when orthodontic consequences need to be considered. To evaluate the effect of this condition, questionnaires of dentists and dental professionals have been carried out in various countries, including those in Europe, Australia and New Zealand, Malaysia, Iraq, Iran and Saudi Arabian. These have generally revealed that MIH has been frequently encountered in clinical practice, particularly by dental professionals who treat children and that there is a need for further training for the condition. To date dental clinicians' concerns regarding MIH have not been extensively assessed in Egypt.

详细描述

In 1970, this condition has been first described as a hypomineralization of the permanent first molars (PFMs) but was consistently referred to it as non-fluoride hypomineralization.

In 2000, there were four presentations that described the same types of developmental defects of dental enamel affecting the first permanent molars (FPM) at the European Academy of Pediatric Dentistry Congress. These reports called the condition hypomineralized first permenet molars FPM, idiopathic enamel hypomineralization in FPM, non-fluoride hypomineralisation in FPM and cheese molars. This was not a new condition. It had been recognized previously but the congress focused on the fact that it has multiple names and that this could conceivably lead to confusion.

In 2001, it has been desirable to use one name that has no reference to any possible etiological factor. So the term "molar-incisor hypomineralization" (MIH) was adopted by Weerheijm to describe these developmental defects and he gave it a definition as "hypomineralization of systemic origin of 1-4 FPM, frequently associated with affected incisors".

In 2003, it was suggested that any examination for MIH should be undertaken on clean wet teeth and optimum at the age of 8-years, as at this age all permanent first molars(PFMs) and most of the incisors will have erupted. The MIH diagnostic criteria are defined using the modified defect of dental enamel (DDE) index, based on criteria by Weerheijm.

Degree of MIH severity Modified DDE index (FDI 1992) Mild degree:- 30% of enamel surface area affected by MIH Moderate degree:- 31 - 49% of enamel surface area affected by MIH Severe degree:- 50% of enamel surface area affected by MIH

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Males and females.
  • Dental students should be at the fifth year.
  • All participants should be Egyptians.

排除标准

  • Dentists or dental students who refuse to participate in the study.
  • Any dentist without the Egyptian nationality even if they are studying in Egyptian universities or working in Egypt.

结局指标

主要结局

knowledge of Egyptian dental practitioners regarding molar-incisor hypomineralization

时间窗: 1 year

The tool used for measuring the primary outcome is a self-administered questionnaire that was fulfilled by the study participants

次要结局

未报告次要终点

研究者

发起方
Alaa Mohammed Yehia
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Alaa Mohammed Yehia

Principal Investigator

Ain Shams University

研究点 (1)

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