Early vs. late initiation of continuous renal replacement therapy in patient suffering from septic shock and acute renal failure

Not Applicable

• Conditions: Septic shock; Acute kidney injury; Renal and Urogenital - Kidney disease

• Registration Number: ACTRN12612000297820
• Lead Sponsor: Shum Hoi Ping

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-03-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

1.Severe sepsis (defined based on ACCP/ SCCM criteria, ie Systemic Inflammatory Response Syndrome in the presence of suspected or known infection, leading to organ dysfunction), and
2.Acute kidney injury (defined based on RIFLE criteria, Injury” grade or above, who required CRRT), and
3.Presence of shock (defined as mean arterial pressure <=65mmHg and required vasopressor support), either at the start or during CRRT

Exclusion Criteria

1.Presence of Chronic kidney disease stage 5 or on regular dialysis support, or
2.Pregnancy

Study & Design

• Study Type: Observational
• Study Design: Not specified