The effect of lignocaine on pain outcomes for women undergoing gynaecological surgery for chronic pelvic pai

Phase 2

Recruiting

• Conditions: Chronic pelvic pain; Anaesthesiology - Pain management; Renal and Urogenital - Other renal and urogenital disorders; Surgery - Other surgery

• Registration Number: ACTRN12621000589886
• Lead Sponsor: Monash health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-05-18
• Last Update Posted: 10 April 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

Women requiring elective operative gynaecological laparoscopy for benign indication as determined and agreed by both the surgeon and the participant.
- Experience of pelvic pain on most days in the preceding 6 months
- Over 18years old and premenopausal at the time of the surgery.
- Participants who understand the conditions of the study and are willing to participate for the duration of study including all follow-up.
- Participants who are capable of, and have given, informed consent to their participation in the study.
- English language or an available translator sufficient to complete the validated quality of life instruments.
- Surgery at Moorabbin Hospital under specialised Endosurgery unit

Exclusion Criteria

- Contraindications to lignocaine (Hypersensitivity; Myasthenia gravis; Severe shock; Supraventricular arrhythmia; Impaired cardiac conduction; Stokes-Adams syndrome or severe degrees of sinoatrial, atrioventricular or intraventricular heart block unless the participant has an artificial pacemaker; Severe renal or liver disease; Use of beta blocker medication e.g. propranolol, metoprolol, atenolol, bisoprolol; Use of Anti-arrhythmic medication e.g. amiodarone, flecainide sotalol, digoxin; Electrolyte abnormalities)
- No significant and persisting pain component to presentation in preceding 6 months.
- Known or suspected malignancy
- Pregnancy
- Requirement for alternative analgesia regimen
- Current/recent use of methadone within 6months of surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified