The RADICAL project: impact of three different diagnostic tests for patients presenting with chest pain.

Not Applicable

Recruiting

Conditions: Coronary artery disease
Angina pectoris
Cardiovascular - Coronary heart disease

Registration Number: ACTRN12616000147482

Lead Sponsor: Royal Perth Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 500

Inclusion Criteria

age 18–85 years with new onset (<3 months) chest pain, suggestive of stable angina pectoris. Our target population includes patients who live within the RPH postcode-allocated referral areas and patients whom live rurally / remotely who would normally be referred to RPH.

Exclusion Criteria

Patients with acute coronary syndrome (ACS) are excluded from this service and should be referred via conventional pathways, such as referral to ED. Other exclusions include: known coronary artery disease, significant cognitive impairment, multiple co-morbidities (involving current input from other clinical specialists), significant valvular heart disease or suspected arrhythmia and advanced renal failure (eGFR <30ml/min). These patients will continue to be assessed in the general cardiology outpatient clinics.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Among patients at intermediate risk of signifciant coronary artery disease, which investigation improves diagnostic certainty (for angina) at 4 weeks?<br><br>'Diagnostic certainty' shall be determined by the physician who reviews the patient in the clinic. The physician shall be asked 'are you certain that the patient's symptoms (angina) are due to coronary artery disease?'; yes, probable, unlikely, or no. <br><br>This shall then be repeated at 4 weeks, following reciept of the results of the test performed. We shall then analyse which test, if any, provided the greatest change in diagnostic certainty between these two time points.[4 weeks from initial clinic assessment.];Among patients at intermediate risk of significant coronary artery disease, which investigation is most cost-effective?<br><br>This analysis shall be performed by assessing which test most frequently provided the highest diagnostic confidence, therefore removing the need for costly repeated testing. [2 years ]

Secondary Outcome Measures