Impact of yoga on cognitive functions, quality of life and social and occupational functions in Schizophrenia

Not Applicable

Recruitment & Eligibility

Inclusion Criteria

1.Patients meeting the diagnostic criteria for schizophrenia in DSM-5

2.CGI score of <= 3 as per treating psychiatrist

3.Males and females between 18 and 45 years

4.Patients without significant extrapyramidal Symptoms with SAS Score of <= 3

5.Patients in whom dose or the antipsychotic has not been changed over the last 6 weeks

6.Able to read, write and speak Kannada or English

7.Patients amenable to neuro-cognitive testing

8.Patients amenable or suitable for the particular yoga/ physical exercise

9.Patient and guardian who are willing to give consent for participation in the study

Exclusion Criteria

1.Patients with co-morbid psychiatric diagnosis

2.Patients currently using psychoactive substance other than nicotine in dependence pattern over the last three months

3.Patients not amenable to neuro-cognitive testing due to poor comprehension or attention span.

4.Patients not amenable or suitable for the particular yoga/ physical exercise due to body structure, joint pains, respiratory difficulties etc.

5. Patients with significant extrapyramidal symptoms SAS score >=4

6. Patients with any uncontrolled physical comorbidity

7. Patients not consenting for the study

Primary Outcome Measures

Name	Time	Method
euro-cognitive functioning, quality of life and soci-occupational functioning.Timepoint: Yoga group will receive 6 weeks of yoga therapy and will be assessed at baseline, at 3 weeks and at the end of 6 week period. <br/ ><br>wait-list group will receive yoga therapy after 6 weeks of waiting period. This group will also undergo 6 weeks of yoga therapy after the waiting period is over. They will be assessed at baseline, 3 weeks, 6 weeks (at the completion of waiting period), 9 weeks (during the yoga therapy) and 12 weeks (at the completion of yoga therapy). <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
Positive and negative symptoms of Schizophrenia <br/ ><br>Extrapyramidal symptomsTimepoint: Yoga group will receive 6 weeks of yoga therapy and will be assessed at baseline, at 3 weeks and at the end of 6 week period. <br/ ><br>wait-list group will receive yoga therapy after 6 weeks of waiting period. This group will also undergo 6 weeks of yoga therapy after the waiting period is over. They will be assessed at baseline, 3 weeks, 6 weeks (at the completion of waiting period), 9 weeks (during the yoga therapy) and 12 weeks (at the completion of yoga therapy). <br/ ><br>