MedPath

Blood Pressure and Cardiac Autonomic Adaptations to Isometric Exercise Training

Not Applicable
Completed
Conditions
Hypertension
Registration Number
NCT05025202
Lead Sponsor
Canterbury Christ Church University
Brief Summary

A randomized, sham-controlled intervention measuring the effects of isometric exercise training (IET) on blood pressure and cardiac autonomics.

IET has been proven effective in a plethora of randomized trials, but very little research has employed a sham-controlled design. This researched involved the recruitment of 30 participants who completed a 4 week IET intervention, sham control of the IET intervention, or a non-intervention control period. Pre and post blood pressure and cardiac autonomic measures were acquired and analysed.

The hypothesis of this trial was a significant effect of IET on blood pressure, with no such effects following the sham control or normal control interventions.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Healthy with no significant health conditions contraindicating exercise
  • Over 18 years of age
  • Physically inactive
Exclusion Criteria
  • Achieving current physical activity guidelines
  • Abnormal resting ECG
  • under 18

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Blood pressure (systolic, diastolic and mean BP)At the end of the intervention (post 4 weeks)

Resting office blood pressure measured at brachial artery

Cardiac autonomics measured at HRVAt the end of the intervention (post 4 weeks)

LF and HF power spectral measures

Secondary Outcome Measures
NameTimeMethod
continuous 5-minute blood pressure (systolic, diastolic and mean BP)At the end of the intervention (post 4 weeks)

5 minute mean of resting blood pressure measured beat-to-beat

Trial Locations

Locations (1)

Canterbury Christ Church University

🇬🇧

Canterbury, Kent, United Kingdom

Canterbury Christ Church University
🇬🇧Canterbury, Kent, United Kingdom

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