Blood Pressure and Cardiac Autonomic Adaptations to Isometric Exercise Training
- Conditions
- Hypertension
- Registration Number
- NCT05025202
- Lead Sponsor
- Canterbury Christ Church University
- Brief Summary
A randomized, sham-controlled intervention measuring the effects of isometric exercise training (IET) on blood pressure and cardiac autonomics.
IET has been proven effective in a plethora of randomized trials, but very little research has employed a sham-controlled design. This researched involved the recruitment of 30 participants who completed a 4 week IET intervention, sham control of the IET intervention, or a non-intervention control period. Pre and post blood pressure and cardiac autonomic measures were acquired and analysed.
The hypothesis of this trial was a significant effect of IET on blood pressure, with no such effects following the sham control or normal control interventions.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Healthy with no significant health conditions contraindicating exercise
- Over 18 years of age
- Physically inactive
- Achieving current physical activity guidelines
- Abnormal resting ECG
- under 18
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Blood pressure (systolic, diastolic and mean BP) At the end of the intervention (post 4 weeks) Resting office blood pressure measured at brachial artery
Cardiac autonomics measured at HRV At the end of the intervention (post 4 weeks) LF and HF power spectral measures
- Secondary Outcome Measures
Name Time Method continuous 5-minute blood pressure (systolic, diastolic and mean BP) At the end of the intervention (post 4 weeks) 5 minute mean of resting blood pressure measured beat-to-beat
Trial Locations
- Locations (1)
Canterbury Christ Church University
🇬🇧Canterbury, Kent, United Kingdom
Canterbury Christ Church University🇬🇧Canterbury, Kent, United Kingdom