Investigation of the effect of pentoxifylline on the prevention of radio contrast nephropathy
Phase 3
- Conditions
- Kidney disorders caused by contrast material following angiography.
- Registration Number
- IRCT20161219031464N4
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 192
Inclusion Criteria
The criteria for entering the study include patients who are candidates for angiography with cardiac service indications and will be admitted to cardiac service.
Exclusion Criteria
patients with stage 5 CKD,
kidney transplantation,
patients with renal insufficiency with a GFR below 30
patients with a history of allergy to pentoxifylline according to history.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum creatinine and creatinine clearance. Timepoint: Serum creatinine and clearance creatinine of patients will be tested the day before and the next day and 48 hours later. Method of measurement: blood and urine sample examination.;C reactive protein. Timepoint: The day before and after angiography. Method of measurement: Blood test.;Proteinuria. Timepoint: The day before and after angiography. Method of measurement: Urine examination.
- Secondary Outcome Measures
Name Time Method