The effect of modulating gut microflora on clinical outcome in elective surgical patients.

Completed

• Conditions: Signs and Symptoms: Sepsis; Signs and Symptoms; Sepsis

• Registration Number: ISRCTN15806146
• Lead Sponsor: Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

Using bacterial translocation as the primary end point for sample size calculation, if the sample size in each of the 4 groups is 20, alpha=0.05 (2-tailed) a chi-square test will have 80% power to detect a difference in proportions.

Exclusion Criteria

Failure to obtain informed consent, patients with co-existing infections, patients on antibiotics in the previous 2 weeks before recruitment and patients with severe hepatic or renal failure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified