ISRCTN15806146CompletedNot Applicable
The effect of modulating gut microflora on clinical outcome in elective surgical patients.
Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)0 sites80 target enrollmentStarted: September 30, 2005Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 80
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •Using bacterial translocation as the primary end point for sample size calculation, if the sample size in each of the 4 groups is 20, alpha=0.05 (2-tailed) a chi-square test will have 80% power to detect a difference in proportions.
Exclusion Criteria
- •Failure to obtain informed consent, patients with co-existing infections, patients on antibiotics in the previous 2 weeks before recruitment and patients with severe hepatic or renal failure.
Investigators
Similar Trials
Completed
Not Applicable
Clinical study on changes in gut microbiota and the effect of bifidobacterium administration in postoperative patients with esophageal canceresophageal cancerJPRN-UMIN000048189agoya City University Graduate School of Medical Sciences15
Recruiting
Phase 3
Targeting the gut microbiome as a treatment for Primary Sclerosing Cholangitis: The Queensland Clinical Network StudyPrimary Sclerosing CholangitisACTRN12621000792820Princess Alexandra Hospital34
Not yet recruiting
Unknown
Exploratory study of the effect on gut microbiota by ingestion of oligosaccharide.Healthy adultJPRN-UMIN000052735Meiji Co., Ltd.49
Completed
Phase 1
Assessment of the influence of the gut microbiome on tacrolimus pharmacokinetics in healthy volunteersPharmacokinetic trial in healthy volunteersDRKS00032072niversitätsklinikum Heidelberg, Im Wege der Auftragsverwaltung für die Universität Heidelberg, Medizinische Fakultät Heidelberg20
Recruiting
Not Applicable
Exploring the modulatory effects of gut microbiota on cholangiocarcinoma progression in a patient-derived organoid modelC22.1Intrahepatic bile duct carcinomaCholangiocarcinomaDRKS00033188nimedizin Mainz, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie20